N3-C2-NHS ester

TargetMol
Product Code: TAR-T18465
Supplier: TargetMol
CodeSizePrice
TAR-T18465-100mg100mgEnquire
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TAR-T18465-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
N3-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker employed for the synthesis of ADCs.
CAS:
850180-76-6
Molecular Weight:
212.1628
Purity:
0.98
SMILES:
[N-]=[N+]=NCCC(=O)ON1C(=O)CCC1=O

References

Gregson SJ, et al. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.