DiAzKs

TargetMol
Product Code: TAR-T18999
Supplier: TargetMol
CodeSizePrice
TAR-T18999-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T18999-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
H-L-Photo-lysine, a photo-cross-linker, is a diazirine-containing lysine amino acid. It can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells.
CAS:
1253643-88-7
Molecular Weight:
272.3
Purity:
0.98
SMILES:
C(COC(NCCCC[C@@H](C(O)=O)N)=O)C1(C)N=N1

References

Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12(2):70-2. Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11803-8. Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12(12):1854-7.