G-Glu-Glu
| Code | Size | Price |
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| TAR-T19727-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T19727-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
G-Glu-Glu is an endogenous constituent of the brain. G-Glu-Glu activates N-methyl-D-aspartate receptors in rats.
CAS:
1116-22-9
Molecular Weight:
276.24
Purity:
0.98
SMILES:
[C@H](NC(CC[C@@H](C(O)=O)N)=O)(CCC(O)=O)C(O)=O
References
Orwar O, Li X, Andin? P, Bergstr?m CM, Hagberg H, Folestad S, Sandberg M. Increased intra- and extracellular concentrations of gamma-glutamylglutamate and related dipeptides in the ischemic rat striatum: involvement of glutamyl transpeptidase. J Neurochem. 1994 Oct;63(4):1371-6. PubMed PMID: 7931288.
Li X, Orwar O, Revesj? C, Sandberg M. Gamma-glutamyl peptides and related amino acids in rat hippocampus in vitro: effect of depolarization and gamma-glutamyl transpeptidase inhibition. Neurochem Int. 1996 Aug;29(2):121-8. PubMed PMID: 8837040.
Tsukamoto T, Flanary JM, Rojas C, Slusher BS, Valiaeva N, Coward JK. Phosphonate and phosphinate analogues of N-acylated gamma-glutamylglutamate. potent inhibitors of glutamate carboxypeptidase II. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2189-92. PubMed PMID: 12127534.
Varga V, Jan?ky R, Holopainen I, Oja SS, Akerman KE. Endogenous gamma-L-glutamylglutamate is a partial agonist at the N-methyl-D-aspartate receptors in cultured cerebellar granule cells. Neurochem Res. 1995 Dec;20(12):1471-6. PubMed PMID: 8789610.