Janumet

TargetMol
Product Code: TAR-T20028
Supplier: TargetMol
CodeSizePrice
TAR-T20028-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T20028-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator.
CAS:
1011232-08-8
Molecular Weight:
670.93
Purity:
0.98
SMILES:
C(NC(=N)N)(N(C)C)=N.Cl.P(=O)(O)(O)O.C(F)(F)(F)C=1N2C(CN(C(C[C@@H](CC3=C(F)C=C(F)C(F)=C3)N)=O)CC2)=NN1

References

El-Zaher AA, Elkady EF, Elwy HM, Saleh MAEM. A Versatile Liquid Chromatographic Method for the Simultaneous Determination of Metformin, Sitagliptin, Simvastatin, and Ezetimibe in Different Dosage Forms. J AOAC Int. 2018 Mar 1;101(2):401-409. doi: 10.5740/jaoacint.17-0050. Epub 2017 Jul 27. PubMed PMID: 28748781. Lotfy HM, Mohamed D, Mowaka S. A comparative study of smart spectrophotometric methods for simultaneous determination of sitagliptin phosphate and metformin hydrochloride in their binary mixture. Spectrochim Acta A Mol Biomol Spectrosc. 2015;149:441-51. doi: 10.1016/j.saa.2015.04.076. Epub 2015 Apr 30. PubMed PMID: 25978011. El-Bagary RI, Elkady EF, Ayoub BM. Spectroflourometric and spectrophotometric methods for the determination of sitagliptin in binary mixture with metformin and ternary mixture with metformin and sitagliptin alkaline degradation product. Int J Biomed Sci. 2011 Mar;7(1):62-9. PubMed PMID: 23675222; PubMed Central PMCID: PMC3614813. El-Bagary RI, Elkady EF, Ayoub BM. Liquid chromatographic determination of sitagliptin either alone or in ternary mixture with metformin and sitagliptin degradation product. Talanta. 2011 Jul 15;85(1):673-80. doi: 10.1016/j.talanta.2011.04.051. Epub 2011 Apr 27. PubMed PMID: 21645757.