Citrazinic acid
| Code | Size | Price |
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| TAR-T20863-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T20863-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Citrazinic acid could inhibit 3-dehydroquinate dehydratase from Mycobacterium tuberculosis. It was also used to synthesize the derivatives of pyrimidinones and oxazinones.
CAS:
99-11-6
Formula:
C6H5NO4
Molecular Weight:
155.11
Purity:
0.98
SMILES:
O=C(O)C1=CC(=O)NC(O)=C1
References
Sarkar S, Chowdhury J, Dutta S, Pal T. A pH dependent Raman and surface enhanced Raman spectroscopic studies of citrazinic acid aided by theoretical calculations. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Dec 5;169:108-15. doi: 10.1016/j.saa.2016.06.023. Epub 2016 Jun 16. PubMed PMID: 27344521.
Hossan AS, Abu-Melha HM, Al-Omar MA, Amr Ael-G. Synthesis and antimicrobial activity of some new pyrimidinone and oxazinone derivatives fused with thiophene rings using 2-chloro-6-ethoxy-4-acetylpyridine as starting material. Molecules. 2012 Nov 19;17(11):13642-55. doi: 10.3390/molecules171113642. PubMed PMID: 23165308.
Masoud MS, Ibrahim AA, Khalil EA, El-Marghany A. Spectral properties of some metal complexes derived from uracil-thiouracil and citrazinic acid compounds. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Jul;67(3-4):662-8. Epub 2006 Aug 25. PubMed PMID: 17029947.
Dias MV, Snee WC, Bromfield KM, Payne RJ, Palaninathan SK, Ciulli A, Howard NI, Abell C, Sacchettini JC, Blundell TL. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis. Biochem J. 2011 Jun 15;436(3):729-39. doi: 10.1042/BJ20110002. PubMed PMID: 21410435.