Aminacrine hydrochloride monohydrate
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| TAR-T21280-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T21280-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Aminacrine hydrochloride monohydrate, a highly fluorescent anti-infective dye, is used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.
CAS:
52417-22-8
Formula:
C13H13ClN2O
Molecular Weight:
248.71
Purity:
0.98
SMILES:
Cl.O.N=1C=2C=CC=CC2C(N)=C3C=CC=CC13
References
Cer?n-Carrasco JP, Ruiz J, Vicente C, de Haro C, Bautista D, Z??iga J, Requena A. DFT Simulation of Structural and Optical Properties of 9-Aminoacridine Half-Sandwich Ru(II), Rh(III), and Ir(III) Antitumoral Complexes and Their Interaction with DNA. J Chem Theory Comput. 2017 Aug 8;13(8):3898-3910. doi: 10.1021/acs.jctc.7b00139. Epub 2017 Jul 6. PubMed PMID: 28641006.
Xiao S, Wang T, Ma X, Qin Y, Li X, Zhao Z, Liu X, Wang X, Xie H, Jiang Q, Sun L, Luo B, Shang L, Chen W, Bai Y, Tang M, He M, Wu L, Ma Q, Hou D, He J. Efficacy and safety of a novel acetylcholinesterase inhibitor octohydroaminoacridine in mild-to-moderate Alzheimer's disease: a Phase II multicenter randomised controlled trial. Age Ageing. 2017 Sep 1;46(5):767-773. doi: 10.1093/ageing/afx045. PubMed PMID: 28419192.
Zhou D, Guo S, Zhang M, Liu Y, Chen T, Li Z. Mass spectrometry imaging of small molecules in biological tissues using graphene oxide as a matrix. Anal Chim Acta. 2017 Apr 15;962:52-59. doi: 10.1016/j.aca.2017.01.043. Epub 2017 Jan 31. PubMed PMID: 28231880.
Ishigami-Yuasa M, Watanabe Y, Mori T, Masuno H, Fujii S, Kikuchi E, Uchida S, Kagechika H. Development of WNK signaling inhibitors as a new class of antihypertensive drugs. Bioorg Med Chem. 2017 Jul 15;25(14):3845-3852. doi: 10.1016/j.bmc.2017.05.034. Epub 2017 May 19. PubMed PMID: 28566208.