CHEC-9
| Code | Size | Price |
|---|
| TAR-T23880-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T23880-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
CHEC-9 is an orally available peptide. It also has anti-inflammatory.
CAS:
714912-53-5
Molecular Weight:
918.99
Purity:
0.98
SMILES:
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CCC(N)=O)=O)C)=O)C)=O)CO)=O)C)=O)CCC(O)=O)=O)NC([C@H](CS)N)=O
References
Cunningham TJ, Yao L, Oetinger M, Cort L, Blankenhorn EP, Greenstein JI. Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis. J Neuroinflammation. 2006 Sep 11;3:26. PubMed PMID: 16965627; PubMed Central PMCID: PMC1592473.
Cunningham TJ, Maciejewski J, Yao L. Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9. J Neuroinflammation. 2006 Sep 11;3:25. PubMed PMID: 16965626; PubMed Central PMCID: PMC1624820.
Chen S, Yao L, Cunningham TJ. Secreted phospholipase A2 involvement in neurodegeneration: differential testing of prosurvival and anti-inflammatory effects of enzyme inhibition. PLoS One. 2012;7(6):e39257. doi: 10.1371/journal.pone.0039257. Epub 2012 Jun 15. PubMed PMID: 22720084; PubMed Central PMCID: PMC3376100.
Cunningham TJ, Greenstein JI, Loewenstern J, Degermentzidis E, Yao L. Anti-inflammatory peptide regulates the supply of heat shock protein 70 monomers: implications for aging and age-related disease. Rejuvenation Res. 2015 Apr;18(2):136-44. doi: 10.1089/rej.2014.1620. PubMed PMID: 25485461; PubMed Central PMCID: PMC4403226.