GR-125487
| Code | Size | Price |
|---|
| TAR-T24101-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24101-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
GR-125487 is a 5-HT4R partial agonist. It also has favorable ADME properties and good in vivo efficacy.
CAS:
2231302-46-6
Molecular Weight:
409.53
Purity:
0.98
SMILES:
CC(C)C1=NN2C(C=CC=C2C3=NN=C(C4CCN(CC5CCOCC5)CC4)O3)=C1
References
Ramakrishna Nirogi, Abdul Rasheed Mohammed, Anil K. Shinde, Shankar Reddy Gagginapally, Durga Malleshwari Kancharla, Vanaja Reddy Middekadi, Narsimha Bogaraju, Srinivasa Rao Ravella, Pooja Singh, Sumit Raosaheb Birangal, Ramkumar Subramanian, Raghava Choudary Palacharla, Vijay Benade, Nageswararao Muddana, and Pradeep Jayarajan. Synthesis, Structure?Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists. Publication Date (Web): May 15, 2018 (Article) doi: 10.1021/acs.jmedchem.8b00457