Mevinolinic acid
| Code | Size | Price |
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| TAR-T24461-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24461-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Mevinolinic acid is an active metabolite of Lovastatin. Lovastatin is an HMG-CoA reductase inhibitor.
CAS:
75225-51-3
Molecular Weight:
422.562
Purity:
0.98
SMILES:
[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC |c:6,9|
References
Bizukojc M, Pawlak M, Boruta T, Gonciarz J. Effect of pH on biosynthesis of lovastatin and other secondary metabolites by Aspergillus terreus ATCC 20542. J Biotechnol. 2012 Dec 31;162(2-3):253-61. doi: 10.1016/j.jbiotec.2012.09.007. Epub 2012 Sep 17. PubMed PMID: 22995742.
Boruta T, Bizukojc M. Induction of secondary metabolism of Aspergillus terreus ATCC 20542 in the batch bioreactor cultures. Appl Microbiol Biotechnol. 2016 Apr;100(7):3009-22. doi: 10.1007/s00253-015-7157-1. Epub 2015 Nov 25. PubMed PMID: 26603760; PubMed Central PMCID: PMC4786612.
Bizukojc M, Ledakowicz S. Simultaneous biosynthesis of (+)-geodin by a lovastatin-producing fungus Aspergillus terreus. J Biotechnol. 2007 Dec 1;132(4):453-60. Epub 2007 Jul 10. PubMed PMID: 17689800.
Boruta T, Bizukojc M. Culture-based and sequence-based insights into biosynthesis of secondary metabolites by Aspergillus terreus ATCC 20542. J Biotechnol. 2014 Apr 10;175:53-62. doi: 10.1016/j.jbiotec.2014.01.038. Epub 2014 Feb 15. PubMed PMID: 24534845.