TargetMol

MK-8282

Product Code:
 
TAR-T24479
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T24479-100mg100mgEnquire
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TAR-T24479-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
MK-8282 is an effective G-Protein-Coupled Receptor 119 agonist for the treatment of Type 2 Diabetes.
CAS:
T24479
Molecular Weight:
503.92
Purity:
0.98
SMILES:
CC1(CC1)OC(N(C[C@@H]2COC3)C[C@@H]3[C@@]2(O)OC4=NC=NC(NC5=CC=C(C=C5Cl)C#N)=C4F)=O

References

Discovery of MK-8282 as a Potent G-Protein-Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes Santhosh F. Neelamkavil, Andrew W. Stamford, Timothy Kowalski, Dipshikha Biswas, Craig Boyle, Samuel Chackalamannil, Yan Xia, Charles Jayne, Bernard Neustadt, Jinsong Hao, Hong Liu, Xing Dai, Hana Baker, Brian Hawes, Kim O?Neill, Huadong Tang, and William J. Greenlee Publication Date (Web): April 10, 2018 (Letter) doi: 10.1021/acsmedchemlett.8b00073