MK-8282

TargetMol
Product Code: TAR-T24479
Supplier: TargetMol
CodeSizePrice
TAR-T24479-100mg100mgEnquire
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TAR-T24479-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
MK-8282 is an effective G-Protein-Coupled Receptor 119 agonist for the treatment of Type 2 Diabetes.
CAS:
T24479
Molecular Weight:
503.92
Purity:
0.98
SMILES:
CC1(CC1)OC(N(C[C@@H]2COC3)C[C@@H]3[C@@]2(O)OC4=NC=NC(NC5=CC=C(C=C5Cl)C#N)=C4F)=O

References

Discovery of MK-8282 as a Potent G-Protein-Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes Santhosh F. Neelamkavil, Andrew W. Stamford, Timothy Kowalski, Dipshikha Biswas, Craig Boyle, Samuel Chackalamannil, Yan Xia, Charles Jayne, Bernard Neustadt, Jinsong Hao, Hong Liu, Xing Dai, Hana Baker, Brian Hawes, Kim O?Neill, Huadong Tang, and William J. Greenlee Publication Date (Web): April 10, 2018 (Letter) doi: 10.1021/acsmedchemlett.8b00073