Tolypomycin Y
| Code | Size | Price |
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| TAR-T24895-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T24895-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Tolypomycin Y is a naturally occurring ansamycin antibiotic.
CAS:
23412-26-2
Molecular Weight:
822.905
Purity:
0.98
SMILES:
[H][C@]12C[C@@]1([H])C(=O)\C=C(C)/C(=O)NC1=CC(=N[C@@H]3CC[C@@H](O)O[C@H]3C)c3c4C(=O)[C@](C)(Oc4c(C)c(O)c3C1=O)O\C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@H]2O |w:15.26,c:46,t:8,14|
References
Bellomo P, Brufani M, Marchi E, Mascellani G, Melloni W, Montecchi L, Stanzani L. Synthesis and antibacterial activity of some derivatives of tolypomycinone. Relationship between structure and activity in ansamycins. J Med Chem. 1977 Oct;20(10):1287-91. PubMed PMID: 333113.
Stanzani L, Venturini AP, Mantovani V. A new tolypomycin-Y derivative: in vitro and in vivo antimicrobial activity. J Antibiot (Tokyo). 1978 Nov;31(11):1195-200. PubMed PMID: 721713.
Hasegawa T. Tolypomycin, a new antibiotic. VII. Assay method for tolypomycin Y. J Antibiot (Tokyo). 1972 Jan;25(1):25-9. PubMed PMID: 5010642.
Marshall VP, Cialdella JI, Ohlmann GM, Gray GD. MIC values do not predict the intraphagocytic killing of Staphylococcus aureus by naphthalenic ansamycins. J Antibiot (Tokyo). 1983 Nov;36(11):1549-60. PubMed PMID: 6140253.