Troponin I (104-115)
| Code | Size | Price |
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| TAR-T24901-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T24901-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Troponin I is a cardiac and skeletal muscle protein useful in the laboratory diagnosis of a heart attack. Troponin I is a part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place.
CAS:
98353-69-6
Molecular Weight:
1550.93
Purity:
0.98
SMILES:
C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC(CNC(C)=O)=O)CCCCN)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCC1)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)CCC3
References
Tanaka H, Takeya Y, Doi T, Yumoto F, Tanokura M, Ohtsuki I, Nishita K, Ojima T. Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I. FEBS J. 2005 Sep;272(17):4475-86. PubMed PMID: 16128816.
Busche MN, Pavlov V, Takahashi K, Stahl GL. Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin. Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1853-9. doi: 10.1152/ajpheart.00049.2009. Epub 2009 Sep 11. PubMed PMID: 19749170; PubMed Central PMCID: PMC2781373.
Schachat F, Brandt PW. The troponin I: inhibitory peptide uncouples force generation and the cooperativity of contractile activation in mammalian skeletal muscle. J Muscle Res Cell Motil. 2013 May;34(2):83-92. doi: 10.1007/s10974-013-9336-y. Epub 2013 Jan 23. PubMed PMID: 23340900.
Ngai SM, Pearlstone JR, Farah CS, Reinach FC, Smillie LB, Hodges RS. Structural and functional studies on Troponin I and Troponin C interactions. J Cell Biochem. 2001 Jun 26-Jul 25;83(1):33-46. Erratum in: J Cell Biochem 2002;84(4):847. PubMed PMID: 11500952.