(18F)LBT 999

TargetMol
Product Code: TAR-T24956
Supplier: TargetMol
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TAR-T24956-100mg100mgEnquire
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TAR-T24956-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
(18F)LBT 999 is a positron emission tomography (PET) tracer, used for the quantification of the dopamine transporter (DAT) in the healthy rat brain.
CAS:
940949-46-2
Molecular Weight:
330.434
Purity:
0.98
SMILES:
[H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(C)cc1)C(=O)OC)N2C\C=C\C[18F] |TLB:9:7:20:2.3,THB:16:6:20:2.3|

References

Peyronneau MA, Saba W, Doll? F, Goutal S, Coulon C, Bottlaender M, Valette H. Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling: part II: Metabolism studies. Nucl Med Biol. 2012 Apr;39(3):347-59. doi: 10.1016/j.nucmedbio.2011.09.006. Epub 2011 Dec 11. PubMed PMID: 22154687. Saba W, Peyronneau MA, Doll? F, Goutal S, Bottlaender M, Valette H. Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling Part I: PET studies. Nucl Med Biol. 2012 Feb;39(2):227-33. doi: 10.1016/j.nucmedbio.2011.08.003. Epub 2011 Oct 26. PubMed PMID: 22033025. S?rri?re S, Tauber C, Vercouillie J, Guilloteau D, Deloye JB, Garreau L, Galineau L, Chalon S. In vivo PET quantification of the dopamine transporter in rat brain with [??F]LBT-999. Nucl Med Biol. 2014 Jan;41(1):106-13. doi: 10.1016/j.nucmedbio.2013.09.007. Epub 2013 Oct 8. PubMed PMID: 24210285.