Hemorphin 4
| Code | Size | Price |
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| TAR-T25490-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T25490-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Hemorphin 4 is an endogenous opioid peptide of the hemorphin family which has antinociceptive properties and is derived from the β-chain of hemoglobin in the bloodstream.
CAS:
103930-64-9
Molecular Weight:
565.62
Purity:
0.98
SMILES:
C([C@H](NC(=O)[C@H]1N(C([C@H](CC2=CC=C(O)C=C2)N)=O)CCC1)C(N[C@@H]([C@@H](C)O)C(O)=O)=O)C=3C=4C(NC3)=CC=CC4
References
Sanderson K, Andr?n PE, Caprioli RM, Nyberg F. In vitro metabolism of LVV-hemorphin-7 in human plasma studied by reversed-phase high-performance liquid chromatography and micro-electrospray mass spectrometry. J Chromatogr A. 1996 Aug 30;743(1):207-12. PubMed PMID: 8817883.
Liebmann C, Schrader U, Brantl V. Opioid receptor affinities of the blood-derived tetrapeptides hemorphin and cytochrophin. Eur J Pharmacol. 1989 Aug 3;166(3):523-6. PubMed PMID: 2553436.
Yang YR, Chiu TH. Opioid and antiopioid actions of Tyr-MIF-1, Tyr-W-MIF-1 and hemorphin-4 on rat locus coeruleus neurons: intracellular recording in vitro. Chin J Physiol. 1997 Sep 30;40(3):131-5. PubMed PMID: 9434888.
Zadina JE, Kastin AJ, Kersh D, Wyatt A. Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum. Life Sci. 1992;51(11):869-85. PubMed PMID: 1355851.