Kinamycin C
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TAR-T25582-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
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TAR-T25582-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Kinamycin C is a bacterial metabolite used as an anticancer agent.
CAS:
35303-08-3
Molecular Weight:
496.428
Purity:
0.98
SMILES:
CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@](C)(O)[C@H](OC(C)=O)c2c1c1c(c2=[N+]=[N-])c(=O)c2c(O)cccc2c1=O
References
Nicolaou KC, Li H, Nold AL, Pappo D, Lenzen A. Total synthesis of kinamycins C, F, and J. J Am Chem Soc. 2007 Aug 29;129(34):10356-7. Epub 2007 Aug 4. PubMed PMID: 17676854.
Omura S, Nakagawa A, Yamada H, Hata T, Furusaki A. Structures and biological properties of Kinamycin A, B, C, and D. Chem Pharm Bull (Tokyo). 1973 May;21(5):931-40. PubMed PMID: 4727361.
Lei X, Porco JA Jr. Total synthesis of the diazobenzofluorene antibiotic (-)-kinamycin C1. J Am Chem Soc. 2006 Nov 22;128(46):14790-1. PubMed PMID: 17105273.
Hasinoff BB, Wu X, Yalowich JC, Goodfellow V, Laufer RS, Adedayo O, Dmitrienko GI. Kinamycins A and C, bacterial metabolites that contain an unusual diazo group, as potential new anticancer agents: antiproliferative and cell cycle effects. Anticancer Drugs. 2006 Aug;17(7):825-37. PubMed PMID: 16926632.