Lasiocarpine N-oxide
| Code | Size | Price |
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| TAR-T25634-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25634-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry.
CAS:
127-30-0
Molecular Weight:
427.494
Purity:
0.98
SMILES:
[H][C@@]12[C@H](CCN1(=O)CC=C2COC(=O)[C@@](O)([C@@H](C)OC)C(C)(C)O)OC(=O)C(\C)=C/C |c:9|
References
Xia Q, Zhao Y, Von Tungeln LS, Doerge DR, Lin G, Cai L, Fu PP. Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity. Chem Res Toxicol. 2013 Sep 16;26(9):1384-96. doi: 10.1021/tx400241c. Epub 2013 Aug 26. PubMed PMID: 23937665.
He X, Xia Q, Woodling K, Lin G, Fu PP. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991. doi: 10.1016/j.jfda.2017.09.001. Epub 2017 Sep 19. PubMed PMID: 28987376.
PETERSON JE. EFFECTS OF THE PYRROLIZIDINE ALKALOID, LASIOCARPINE N-OXIDE, ON NUCLEAR AND CELL DIVISION IN THE LIVER RATS. J Pathol Bacteriol. 1965 Jan;89:153-71. PubMed PMID: 14263458.
Field RA, Stegelmeier BL, Colegate SM, Brown AW, Green BT. An in vitro comparison of the cytotoxic potential of selected dehydropyrrolizidine alkaloids and some N-oxides. Toxicon. 2015 Apr;97:36-45. doi: 10.1016/j.toxicon.2015.02.001. Epub 2015 Feb 7. PubMed PMID: 25666399.