Lemnalol
| Code | Size | Price |
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| TAR-T25658-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T25658-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Lemnalol is a natural marine compound from the Formosan soft coral Lemnalia cervicorni. It exhibits anti-inflammatory and analgesic effects in carrageenan-injected rats.
CAS:
82570-34-1
Formula:
C15H24O
Molecular Weight:
220.356
Purity:
0.98
SMILES:
[H][C@@]12C[C@@H](O)C(=C)[C@@]3([H])[C@]1([H])[C@@H](CC[C@@]23C)C(C)C |@@:16,TLB:15:14:9:2.3.5,2:1:7:11.13.12,5:7:1:11.13.12,THB:16:11:7:1,13:14:9:2.3.5|
References
Jean YH, Chen WF, Duh CY, Huang SY, Hsu CH, Lin CS, Sung CS, Chen IM, Wen ZH. Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni. Eur J Pharmacol. 2008 Jan 14;578(2-3):323-31. Epub 2007 Sep 20. PubMed PMID: 17916350.
Lin YC, Huang SY, Jean YH, Chen WF, Sung CS, Kao ES, Wang HM, Chakraborty C, Duh CY, Wen ZH. Intrathecal lemnalol, a natural marine compound obtained from Formosan soft coral, attenuates nociceptive responses and the activity of spinal glial cells in neuropathic rats. Behav Pharmacol. 2011 Dec;22(8):739-50. doi: 10.1097/FBP.0b013e32834d0ecb. PubMed PMID: 22067479.
Lee HP, Huang SY, Lin YY, Wang HM, Jean YH, Wu SF, Duh CY, Wen ZH. Soft coral-derived lemnalol alleviates monosodium urate-induced gouty arthritis in rats by inhibiting leukocyte infiltration and iNOS, COX-2 and c-Fos protein expression. Mar Drugs. 2013 Jan 10;11(1):99-113. doi: 10.3390/md11010099. PubMed PMID: 23306170; PubMed Central PMCID: PMC3564160.
Lee HP, Lin YY, Duh CY, Huang SY, Wang HM, Wu SF, Lin SC, Jean YH, Wen ZH. Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. J Pharm Pharmacol. 2015 Feb;67(2):274-85. doi: 10.1111/jphp.12331. Epub 2014 Dec 31. PubMed PMID: 25557511.