Leucyl-phenylalanine amide
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| TAR-T25685-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T25685-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Leucyl-phenylalanine amide is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to produce amyloid β-peptide (Aβ) which is the major causative agent in Alzheimer disease (AD).
CAS:
38678-60-3
Formula:
C15H23N3O2
Molecular Weight:
277.36
Purity:
0.98
SMILES:
C([C@H](NC([C@H](CC(C)C)N)=O)C(N)=O)C1=CC=CC=C1
References
Peyton D, Breslow E. Use of perdeuterated peptides in NMR studies of neurophysin-hormone interaction: demonstration of peptide-specific changes in neurophysin resonances. Biochem Biophys Res Commun. 1985 May 16;128(3):1211-8. PubMed PMID: 4004858.