PYX 2
| Code | Size | Price |
|---|
| TAR-T26008-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26008-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
PYX 2 is used as a neuropeptide Y receptor antagonist.
CAS:
146999-93-1
Molecular Weight:
1698.64
Purity:
0.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)c(Cc2c(Cl)cccc2Cl)c1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)c(Cc2c(Cl)cccc2Cl)c1)C(N)=O
References
Beck B, Stricker-Krongrad A, Musse N, Nicolas JP, Burlet C. Putative neuropeptide Y antagonist failed to decrease overeating in obese Zucker rats. Neurosci Lett. 1994 Nov 7;181(1-2):126-8. PubMed PMID: 7898751.
Lee MC, Lawson DC, Pappas TN. Neuropeptide Y functions as a physiologic regulator of cephalic phase acid secretion. Regul Pept. 1994 Aug 4;52(3):227-34. PubMed PMID: 7800854.
Leibowitz SF, Xuereb M, Kim T. Blockade of natural and neuropeptide Y-induced carbohydrate feeding by a receptor antagonist PYX-2. Neuroreport. 1992 Nov;3(11):1023-6. PubMed PMID: 1482761.
Palea S, Corsi M, Rimland JM, Trist DG, Ratti E. Failure of the putative neuropeptide Y antagonists, benextramine and PYX-2, to inhibit Y2 receptors in rat isolated prostatic vas deferens. Br J Pharmacol. 1995 Nov;116(5):2401-6. PubMed PMID: 8581275; PubMed Central PMCID: PMC1909051.