Allosamidin
| Code | Size | Price |
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| TAR-T26595-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26595-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Allosamidin, a chitinase inhibitor and typical secondary metabolite of Streptomyces, may be used as a pesticide and anti-asthmatic agent.
CAS:
103782-08-7
Molecular Weight:
622.625
Purity:
0.98
SMILES:
[H][C@@]12OC(=N[C@]1([H])[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]3NC(C)=O)[C@@H](O)[C@H]1NC(C)=O)[C@H]2CO)N(C)C |c:3|
References
Suzuki S, Nakanishi E, Ohira T, Kawachi R, Nagasawa H, Sakuda S. Chitinase inhibitor allosamidin is a signal molecule for chitinase production in its producing Streptomyces I. Analysis of the chitinase whose production is promoted by allosamidin and growth accelerating activity of allosamidin. J Antibiot (Tokyo). 2006 Jul;59(7):402-9. PubMed PMID: 17025016.
Wang Y, Liu T, Yang Q, Li Z, Qian X. A modeling study for structure features of ?-N-acetyl-D-hexosaminidase from Ostrinia furnacalis and its novel inhibitor allosamidin: species selectivity and multi-target characteristics. Chem Biol Drug Des. 2012 Apr;79(4):572-82. doi: 10.1111/j.1747-0285.2011.01301.x. Epub 2012 Jan 30. PubMed PMID: 22177554.
Suzuki S, Nagasawa H, Sakuda S. Identification of the allosamidin-releasing factor in allosamidin-producing Streptomyces. J Antibiot (Tokyo). 2014 Feb;67(2):195-7. doi: 10.1038/ja.2013.109. Epub 2013 Oct 30. PubMed PMID: 24169800.
Sato Y, Suzuki S, Muraoka S, Kikuchi N, Noda N, Matsumoto T, Inoue H, Nagasawa H, Sakuda S. Preparation of allosamidin and demethylallosamidin photoaffinity probes and analysis of allosamidin-binding proteins in asthmatic mice. Bioorg Med Chem. 2011 May 15;19(10):3054-9. doi: 10.1016/j.bmc.2011.04.012. Epub 2011 Apr 13. PubMed PMID: 21530272.