Ambazone hydrate
| Code | Size | Price |
|---|
| TAR-T26613-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26613-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Ambazone hydrate has anti-cancer activity.
CAS:
07/12/6011
Molecular Weight:
255.3
Purity:
0.98
SMILES:
S=C(N)NN=C1C=CC(=NNC(=N)N)C=C1.O
References
Gutsche W, H?rtl A, Baumgart J, Schulze W. [Antineoplastic activity and toxicity of dihydroambazone in comparison with ambazone (1,4-benzoquinone-guanylhydrazone-thiosemicarbazone)]. Pharmazie. 1990 Jan;45(1):55-7. German. PubMed PMID: 2333315.
Amlacher R, K?hnel HJ, Niemann G, Schulze W. Pharmacokinetics of 14C-ambazone (1,4-benzochinone-guanylhydrazone-14C-thiosemicarbazone) in B6D2F1 mice. Pharmazie. 1986 Feb;41(2):155. PubMed PMID: 3725860.
Choi J, Jee JG. Repositioning of Thiourea-Containing Drugs as Tyrosinase Inhibitors. Int J Mol Sci. 2015 Dec 2;16(12):28534-48. doi: 10.3390/ijms161226114. PubMed PMID: 26633377; PubMed Central PMCID: PMC4691061.
Muresan-Pop M, Braga D, Pop MM, Borodi G, Kacso I, Maini L. Crystal structure and physicochemical characterization of ambazone monohydrate, anhydrous, and acetate salt solvate. J Pharm Sci. 2014 Nov;103(11):3594-3601. doi: 10.1002/jps.24151. Epub 2014 Sep 3. PubMed PMID: 25187325.