AWD12?281
Code | Size | Price |
---|
TAR-T26694-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T26694-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
AWD12-281 is an inhibitor of PDE4.
CAS:
T26694
Molecular Weight:
443.26
Purity:
0.98
SMILES:
OC1=CC=C2C(C(C(C(C3=C(Cl)C=NC=C3Cl)=O)=O)=CN2CC4=CC=C(F)C=C4)=C1
References
Chan AL, Huang HL, Chien HC, Chen CM, Lin CN, Ko WC. Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [(3) H]-rolipram binding in guinea pig tissues. Invest New Drugs. 2008 Oct;26(5):417-24. doi: 10.1007/s10637-008-9114-7. Epub 2008 Feb 9. PubMed PMID: 18264679.
Richter W, Unciuleac L, Hermsdorf T, Kronbach T, Dettmer D. Identification of inhibitor binding sites of the cAMP-specific phosphodiesterase 4. Cell Signal. 2001 Apr;13(4):287-97. PubMed PMID: 11306246.