BB-83698
| Code | Size | Price |
|---|
| TAR-T26749-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26749-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
BB-83698 is a peptide deformylase inhibitor with potent antimicrobial against streptococci and Moraxella catarrhalis strains.
CAS:
325795-25-3
Molecular Weight:
530.66
Purity:
0.98
SMILES:
C(C=1C=C2C(=CC1)OCO2)N3CCN(C([C@@H](NC([C@H](CC4CCCC4)CN(C=O)O)=O)C(C)(C)C)=O)CC3
References
Sangshetti JN, Khan FA, Shinde DB. Peptide deformylase: a new target in antibacterial, antimalarial and anticancer drug discovery. Curr Med Chem. 2015;22(2):214-36. Review. PubMed PMID: 25174923.
Khurdayan V, Bozzo J, Sorbera L. Chronicles in drug discovery. Drug News Perspect. 2005 Jun;18(5):332-6. PubMed PMID: 16193105.
Wang Q, Wang J, Cai Z, Xu W. Prediction of the binding modes between BB-83698 and peptide deformylase from Bacillus stearothermophilus by docking and molecular dynamics simulation. Biophys Chem. 2008 May;134(3):178-84. doi: 10.1016/j.bpc.2008.02.003. Epub 2008 Feb 16. PubMed PMID: 18321635.
Guay DR. Drug forecast - the peptide deformylase inhibitors as antibacterial agents. Ther Clin Risk Manag. 2007 Aug;3(4):513-25. PubMed PMID: 18472972; PubMed Central PMCID: PMC2374925.