BIBP3226
| Code | Size | Price |
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| TAR-T26801-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T26801-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.
CAS:
159013-54-4
Molecular Weight:
473.57
Purity:
0.98
SMILES:
C(C(N[C@@H](C(NCC1=CC=C(O)C=C1)=O)CCCNC(=N)N)=O)(C2=CC=CC=C2)C3=CC=CC=C3
References
Fang Q, Guo J, He F, Peng YL, Chang M, Wang R. In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist. Peptides. 2006 Sep;27(9):2207-13. PubMed PMID: 16762456.
Engstr?m M, Wurster S, Savola JM, Panula P. Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors. Peptides. 2003 Dec;24(12):1947-54. PubMed PMID: 15127947.
Van Liefde, Vanderheyden PM, De Backer JP, Ebinger G, Vauquelin G. Effects of BIBP3226 and BIBP3435 on cytosolic calcium in neuropeptide Y Y1 receptor-transfected Chinese hamster ovary cells and wild type CHO-K1 cells. J Recept Signal Transduct Res. 2001 Feb;21(1):11-23. PubMed PMID: 11693170.
Chen SH, Cheung RT. Intracerebroventricular injection of a neuropeptide Y-Y1 receptor agonist increases while BIBP3226, a Y1 antagonist, reduces the infarct volume following transient middle cerebral artery occlusion in rats. Neuroscience. 2003;116(1):119-26. PubMed PMID: 12535945.