TargetMol

MBRI-001

Product Code:
 
TAR-T27982
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
MBRI-001 is a deuterium-substituted plinabulin derivative and a potent anti-cancer agent with better pharmacokinetic characteristics tand lower toxicity.
CAS:
2054938-28-0
Formula:
C19H20N4O2
Molecular Weight:
337.39
Purity:
0.98
SMILES:
C(\C1=C(C(C)(C)C)N=CN1)(=C\2/C(=O)N/C(=C\C3=CC=CC=C3)/C(=O)N2)/[2H]

References

Ding Z, Cheng H, Wang S, Hou Y, Zhao J, Guan H, Li W. Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1416-1419. doi: 10.1016/j.bmcl.2017.01.096. PubMed PMID: 28228362.