7-Deazainosine
| Code | Size | Price |
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| TAR-T29482-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29482-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
7-Deazainosine is a biochemical.
CAS:
2862-16-0
Molecular Weight:
267.24
Purity:
0.98
SMILES:
O[C@H]1[C@H](N2C3=C(C=C2)C(=O)N=CN3)O[C@H](CO)[C@H]1O
References
Moreau C, Wagner GK, Weber K, Guse AH, Potter BV. Structural determinants for N1/N7 cyclization of nicotinamide hypoxanthine 5'-dinucleotide (NHD+) derivatives by ADP-ribosyl cyclase from aplysia californica: Ca2+-mobilizing activity of 8-substituted cyclic inosine 5'-diphosphoribose analogues in T-lymphocytes. J Med Chem. 2006 Aug 24;49(17):5162-76. PubMed PMID: 16913705.
Leonard P, Ingale SA, Ding P, Ming X, Seela F. Studies on the glycosylation of pyrrolo[2,3-d] pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose: the formation of regioisomers during toyocamycin and 7-deazainosine syntheses. Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):678-94. doi: 10.1080/15257770903091953. PubMed PMID: 20183609.
Ciliberti N, Durini E, Manfredini S, Vertuani S. 7-deazainosine derivatives: synthesis and characterization of 7- and 7,8-substituted pyrrolo [2,3-d]pyrimidine ribonucleosides. Nucleosides Nucleotides Nucleic Acids. 2008 May;27(5):525-33. doi: 10.1080/15257770802089009. PubMed PMID: 18569790.
Al Safarjalani ON, Rais RH, Kim YA, Chu CK, Naguib FN, el Kouni MH. 7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities. Biochem Pharmacol. 2008 Oct 15;76(8):958-66. doi: 10.1016/j.bcp.2008.07.035. Epub 2008 Aug 7. PubMed PMID: 18755159; PubMed Central PMCID: PMC2581922.