7-Deoxyadriamycinol aglycone
| Code | Size | Price |
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| TAR-T29483-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29483-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
7-Deoxyadriamycinol aglycone is an adriamycin metabolite.
CAS:
37818-13-6
Formula:
C21H20O8
Molecular Weight:
400.383
Purity:
0.98
SMILES:
COc1cccc2C(=O)c3c(O)c4C[C@](O)(CCc4c(O)c3C(=O)c12)[C@@H](O)CO
References
Dodion P, Riggs CE Jr, Akman SR, Bachur NR. Effect of hyperthermia on the in vitro metabolism of doxorubicin. Cancer Treat Rep. 1986 May;70(5):625-9. PubMed PMID: 3708610.
Gille L, Nohl H. Analyses of the molecular mechanism of adriamycin-induced cardiotoxicity. Free Radic Biol Med. 1997;23(5):775-82. PubMed PMID: 9296455.
Samuel L. Doxorubicin-induced cardiotoxicity. Postgrad Med J. 1995 May;71(835):318. PubMed PMID: 7596949; PubMed Central PMCID: PMC2398096.
Cummings J, Milstead R, Cunningham D, Kaye S. Marked inter-patient variation in adriamycin biotransformation to 7-deoxyaglycones: evidence from metabolites identified in serum. Eur J Cancer Clin Oncol. 1986 Aug;22(8):991-1001. PubMed PMID: 3770056.