Aluminum phthalocyanine disulfonate disodium
| Code | Size | Price |
|---|
| TAR-T29922-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T29922-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Aluminum phthalocyanine disulfonate sodium, also known as AlPcS2 disodium or AlS2Pc or AlPcS(2a), is a potent photosensitizer, and is potentially useful in cancer sonodynamic therapy and cancer photodynamic therapy. Aluminum phthalocyanine disulfonate is a mixture of regional isomers, in which sulfonate group can be in 3- or 4- position in phenyl ring. Aluminum phthalocyanine disulfonate is also a Coloring Agent; Dermatologic Agent; Fluorescent Dye; Indicators and Reagent; Luminescent Agent; Photosensitizing Agent; Radiation-Sensitizing Agent.
CAS:
68637-19-4
Molecular Weight:
779.05
Purity:
0.98
SMILES:
[Na+].[Na+].[O-]S(=O)(=O)c1ccc2C3=NC(=Nc4n5[Al](Cl)n6c(=NC7=NC(=Nc5c5ccc(cc45)S([O-])(=O)=O)c4ccccc74)c4ccccc4c6=N3)c2c1 |w:13.11,49.54,24.22,20.18,c:8,t:19|
References
Pizova K, Bajgar R, Fillerova R, Kriegova E, Cenklova V, Langova K, Konecny P, Kolarova H. C-MYC and C-FOS expression changes and cellular aspects of the photodynamic reaction with photosensitizers TMPyP and ClAlPcS2. J Photochem Photobiol B. 2015 Jan;142:186-96. doi: 10.1016/j.jphotobiol.2014.12.003. Epub 2014 Dec 9. PubMed PMID: 25545333.
Trinidad AJ, Hong SJ, Peng Q, Madsen SJ, Hirschberg H. Combined concurrent photodynamic and gold nanoshell loaded macrophage-mediated photothermal therapies: an in vitro study on squamous cell head and neck carcinoma. Lasers Surg Med. 2014 Apr;46(4):310-8. doi: 10.1002/lsm.22235. Epub 2014 Mar 20. PubMed PMID: 24648368; PubMed Central PMCID: PMC4142684.
Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y. Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate. Ultrason Sonochem. 2016 Jan;28:161-8. doi: 10.1016/j.ultsonch.2015.07.013. Epub 2015 Jul 14. PubMed PMID: 26384895.
Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y. Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168]. Ultrason Sonochem. 2016 Jun 9. pii: S1350-4177(16)30199-7. doi: 10.1016/j.ultsonch.2016.06.002. [Epub ahead of print] PubMed PMID: 27291696.