Apratoxin C
| Code | Size | Price |
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| TAR-T30106-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30106-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Apratoxin C is a cyanobacterial cyclodepsipeptide as a potent cytotoxin.
CAS:
444885-30-7
Molecular Weight:
826.11
Purity:
0.98
SMILES:
[H][C@]12CSC(=N1)[C@@H](C)[C@@H](O)C[C@H](C)CC(OC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])([C@@H](C)CC)N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)\C(C)=C\2)C(C)C |c:4,t:59,@@:58|
References
Yoshida M, Onda Y, Masuda Y, Doi T. Potent oxazoline analog of apratoxin C: Synthesis, biological evaluation, and conformational analysis. Biopolymers. 2016 Nov 4;106(4):404-14. doi: 10.1002/bip.22781. PubMed PMID: 26584466.
Masuda Y, Suzuki J, Onda Y, Fujino Y, Yoshida M, Doi T. Total synthesis and conformational analysis of apratoxin C. J Org Chem. 2014 Sep 5;79(17):8000-9. doi: 10.1021/jo501130b. Epub 2014 Aug 18. PubMed PMID: 25093538.
Matthew S, Salvador LA, Schupp PJ, Paul VJ, Luesch H. Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam. J Nat Prod. 2010 Sep 24;73(9):1544-52. doi: 10.1021/np1004032. PubMed PMID: 20704304; PubMed Central PMCID: PMC2965600.
Luesch H, Yoshida WY, Moore RE, Paul VJ. New apratoxins of marine cyanobacterial origin from Guam and Palau. Bioorg Med Chem. 2002 Jun;10(6):1973-8. PubMed PMID: 11937357.