Benzoflavine
| Code | Size | Price |
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| TAR-T30377-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30377-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Benzoflavine is a basic yellow acridine dye.
CAS:
477-74-7
Molecular Weight:
313.4
Purity:
0.98
SMILES:
N=1C=2C=C(N)C(=CC2C(C=3C=CC=CC3)=C4C=C(C(N)=CC14)C)C
References
Marsch GA, Carlson BT, Guengerich FP. 7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites. J Biomol Struct Dyn. 2018 Mar;36(4):841-860. doi: 10.1080/07391102.2017.1301270. Epub 2017 Mar 20. PubMed PMID: 28278026; PubMed Central PMCID: PMC5785493.
Lubet RA, Townsend R, Clapper ML, Juliana MM, Steele VE, McCormick DL, Grubbs CJ. 5MeCDDO Blocks Metabolic Activation but not Progression of Breast, Intestine, and Tongue Cancers. Is Antioxidant Response Element a Prevention Target? Cancer Prev Res (Phila). 2016 Jul;9(7):616-23. doi: 10.1158/1940-6207.CAPR-15-0294. Epub 2016 May 5. PubMed PMID: 27150634; PubMed Central PMCID: PMC4930704.
Singh H, Singh JV, Gupta MK, Singh P, Sharma S, Nepali K, Bedi PMS. Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies. Bioorg Med Chem Lett. 2017 Feb 15;27(4):850-854. doi: 10.1016/j.bmcl.2017.01.020. Epub 2017 Jan 10. PubMed PMID: 28117203.
Elbarbry F, Ung A, Abdelkawy K. Studying the Inhibitory Effect of Quercetin and Thymoquinone on Human Cytochrome P450 Enzyme Activities. Pharmacogn Mag. 2018 Jan;13(Suppl 4):S895-S899. doi: 10.4103/0973-1296.224342. Epub 2018 Jan 31. PubMed PMID: 29491651; PubMed Central PMCID: PMC5822518.