BMS-422461
Code | Size | Price |
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TAR-T30522-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30522-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
BMS-422461 is a prodrug of the novel fluoro-substituted camptothecin analog, BMS-286309.
CAS:
T30522
Molecular Weight:
655.66
Purity:
0.98
SMILES:
O=C(O[C@](C1=C(CO2)C(N3CC4=C(CC)C5=CC6=C(OC(F)(F)O6)C=C5N=C4C3=C1)=O)(CC)C2=O)CCNC([C@@H](N)CCCCN)=O
References
Rose WC, Marathe PH, Jang GR, Monticello TM, Balasubramanian BN, Long B, Fairchild CR, Wall ME, Wani MC. Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization. Cancer Chemother Pharmacol. 2006 Jul;58(1):73-85. Epub 2005 Oct 14. PubMed PMID: 16228206.