S-Ruxolitinib
Code | Size | Price |
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TAR-T3066-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3066-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
CAS:
1160597-27-2
Molecular Weight:
306.37
Pathway:
Chromatin/Epigenetic|JAK/STAT signaling|Angiogenesis|Stem Cells
Purity:
0.9975
SMILES:
N#CCC(C1CCCC1)n2cc(cn2)c4ncnc3nccc34
Target:
JAK
References
Quintas-Cardama A, et al. Blood, 2010, 115(15), 3109-3117.