Drimane
| Code | Size | Price |
|---|
| TAR-T31575-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T31575-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activity.
CAS:
5951-58-6
Molecular Weight:
208.389
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](C)[C@H](C)[C@@]1(C)CCCC2(C)C
References
De La Chapa J, Singha PK, Sallaway M, Self K, Nasreldin R, Dasari R, Hart M, Kornienko A, Just J, Smith JA, Bissember AC, Gonzales CB. Novel polygodial analogs P3 and P27: Efficacious therapeutic agents disrupting mitochondrial function in oral squamous cell carcinoma. Int J Oncol. 2018 Dec;53(6):2627-2636. doi: 10.3892/ijo.2018.4585. Epub 2018 Oct 5. PubMed PMID: 30320372; PubMed Central PMCID: PMC6203145.
Kou RW, Du ST, Li YX, Yan XT, Zhang Q, Cao CY, Yin X, Gao JM. Cyathane diterpenoids and drimane sesquiterpenoids with neurotrophic activity from cultures of the fungus Cyathus africanus. J Antibiot (Tokyo). 2019 Jan;72(1):15-21. doi: 10.1038/s41429-018-0106-3. Epub 2018 Oct 16. PubMed PMID: 30327549.
Ma M, Feng J, Wang D, Chen SW, Xu H. Synthesis and Antifungal Activities of Drimane-Amide Derivatives from Sclareol. Comb Chem High Throughput Screen. 2018;21(7):501-509. doi: 10.2174/1386207321666180925164358. PubMed PMID: 30255746.
Gon?alves GEG, Morais TR, Gomes KS, Costa-Silva TA, Tempone AG, Lago JHG, Caseli L. Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface. Bioorg Chem. 2018 Nov 24;84:186-191. doi: 10.1016/j.bioorg.2018.11.048. [Epub ahead of print] PubMed PMID: 30502630.