GYKI-14451 sulfate
| Code | Size | Price |
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| TAR-T32028-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T32028-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
GYKI-14451 (LY-178207) is a synthetic thrombin tripeptide inhibitor with anti-atherosclerotic activity.
CAS:
83861-29-4
Molecular Weight:
551.65
Purity:
0.98
SMILES:
O=S(O)(O)=O.CC(C)(C)OC(N[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)=O.CC(C)(C)OC(N[C@H](CC3=CC=CC=C3)C(N4[C@@H](CCC4)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)=O
References
Barabas E, Szell E, Bajusz S. Screening for fibrinolysis inhibitory effect of synthetic thrombin inhibitors. Blood Coagul Fibrinolysis. 1993 Apr;4(2):243-8. PubMed PMID: 8499562.
Callas DD, Fareed J. Direct inhibition of protein Ca by site directed thrombin inhibitors: implications in anticoagulant and thrombolytic therapy. Thromb Res. 1995 Jun 1;78(5):457-60. PubMed PMID: 7544924.
Callas D, Bacher P, Iqbal O, Hoppensteadt D, Fareed J. Fibrinolytic compromise by simultaneous administration of site-directed inhibitors of thrombin. Thromb Res. 1994 May 1;74(3):193-205. PubMed PMID: 8042188.
Callas D, Iqbal O, Fareed J. Comparison of the anticoagulant activities of thrombin inhibitors as assessed by thromboelastographic analysis. Semin Thromb Hemost. 1995;21 Suppl 4:76-9. PubMed PMID: 8747693.