IVDE77
| Code | Size | Price |
|---|
| TAR-T32240-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32240-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
IVDE77 is the first Ang IV-analogue with the ability to abolish IRAP-availability completely at the cell surface in vitro.
CAS:
T32240
Molecular Weight:
852.05
Purity:
0.98
SMILES:
NC[C@@H](C(C)C)C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N[C@@H](CC1=C(NC2=C1C=CC=C2)C3)C(N3[C@@H](CCC)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)CC5=CC=C(O)C=C5)=O
References
Nikolaou A, Stijlemans B, Laoui D, Schouppe E, Tran HT, Tourw? D, Chai SY, Vanderheyden PM, Van Ginderachter JA. Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages. J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):466-79. doi: 10.1177/1470320313507621. Epub 2014 Feb 14. PubMed PMID: 24532823.
Nikolaou A, Van den Eynde I, Tourw? D, Vauquelin G, T?th G, Mallareddy JR, Poglitsch M, Van Ginderachter JA, Vanderheyden PM. [3H]IVDE77, a novel radioligand with high affinity and selectivity for the insulin-regulated aminopeptidase. Eur J Pharmacol. 2013 Feb 28;702(1-3):93-102. doi: 10.1016/j.ejphar.2013.01.026. Epub 2013 Jan 31. PubMed PMID: 23376157.