Lipid II binder 5107930

TargetMol
Product Code: TAR-T32777
Supplier: TargetMol
CodeSizePrice
TAR-T32777-100mg100mgEnquire
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TAR-T32777-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Lipid II binder 5107930 is a lipid II binder which causes specific upregulation of the vancomycin-resistance associated gene vraX, which is implicated in the cell wall stress stimulon that confers glycopeptide resistance.
CAS:
T32777
Molecular Weight:
570.58
Purity:
0.98
SMILES:
CN(C1=C(C)C(C)=CC=C1)/C=C/C2=C3[N+](CC)=C(/C=C/C=C4CCCCC/4)SC3=CC=C2.[I-]

References

Malin J, Shetty AC, Daugherty SC, de Leeuw EP. Effect of a small molecule Lipid II binder on bacterial cell wall stress. Infect Drug Resist. 2017 Feb 28;10:69-73. doi: 10.2147/IDR.S126254. eCollection 2017. PubMed PMID: 28280373; PubMed Central PMCID: PMC5338996.