L-Topaquinone
| Code | Size | Price |
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| TAR-T32907-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T32907-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
L-Topaquinone is a metabolite of dopaquione, an important intermediate in melanogenesis.
CAS:
135791-48-9
Molecular Weight:
211.17
Purity:
0.98
SMILES:
C([C@@H](C(O)=O)N)C=1C(O)=CC(=O)C(=O)C1
References
Ito S, Wakamatsu K. Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. Photochem Photobiol. 2008 May-Jun;84(3):582-92. doi: 10.1111/j.1751-1097.2007.00238.x. Review. PubMed PMID: 18435614.
Cie?ska M, Labus K, Lewa?czuk M, Ko?lecki T, Liesiene J, Bryjak J. Effective L-Tyrosine Hydroxylation by Native and Immobilized Tyrosinase. PLoS One. 2016 Oct 6;11(10):e0164213. doi: 10.1371/journal.pone.0164213. eCollection 2016. PubMed PMID: 27711193; PubMed Central PMCID: PMC5053437.
Gasowska B, Wojtasek H, Hurek J, Drag M, Nowak K, Kafarski P. Redox reaction between amino-(3,4-dihydroxyphenyl)methyl phosphonic acid and dopaquinone is responsible for the apparent inhibitory effect on tyrosinase. Eur J Biochem. 2002 Aug;269(16):4098-104. Erratum in: Eur J Biochem 2002 Oct;269(20):5101. PubMed PMID: 12180986.
Rahman SF, Gobikrishnan S, Indrawan N, Park SH, Park JH, Min K, Yoo YJ, Park DH. A study on the electrochemical synthesis of L-DOPA using oxidoreductase enzymes: optimization of an electrochemical process. J Microbiol Biotechnol. 2012 Oct;22(10):1446-51. PubMed PMID: 23075798.