MitoNeoD
| Code | Size | Price |
|---|
| TAR-T33410-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33410-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
MitoNeoD is a novel mitochondria-targeted O2(.-) probe that can be used in vivo. It prevents DNA intercalation. MitoNeoD incorporates a carbon-deuterium bond, and enhances O2(.-) selectivity.
CAS:
T33410
Molecular Weight:
853.99
Purity:
0.98
SMILES:
CC(C)(C)CNC1=CC(C(C2=CC=CC=C2)([2H])N(CCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C6=CC(NCC(C)(C)C)=CC=C76)=C7C=C1.[Br-]
References
Jiang L, Xue YJ, Liu WY, Ma M, Wu XR, Wang SZ, Chen YJ. The importance of start codon of nosM in nosiheptide production. Chin J Nat Med. 2015 Nov;13(11):854-860. doi: 10.1016/S1875-5364(15)30089-3. PubMed PMID: 26614460.
Yin S, Jiang H, Chen D, Murchie AI. Substrate recognition and modification by the nosiheptide resistance methyltransferase. PLoS One. 2015 Apr 24;10(4):e0122972. doi: 10.1371/journal.pone.0122972. eCollection 2015. PubMed PMID: 25910005; PubMed Central PMCID: PMC4409310.
Wang Q, Zhang D, Li Y, Zhang F, Wang C, Liang X. Genome shuffling and ribosome engineering of Streptomyces actuosus for high-yield nosiheptide production. Appl Biochem Biotechnol. 2014 Jul;173(6):1553-63. doi: 10.1007/s12010-014-0948-5. Epub 2014 May 15. PubMed PMID: 24828581.
Liu W, Xue Y, Ma M, Wang S, Liu N, Chen Y. Multiple oxidative routes towards the maturation of nosiheptide. Chembiochem. 2013 Sep 2;14(13):1544-7. doi: 10.1002/cbic.201300427. Epub 2013 Aug 12. PubMed PMID: 23939763.