Msh (5-10), cyclic
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| TAR-T33516-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| TAR-T33516-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Msh (5-10), cyclic, as a synthetic peptide, can conjugate with fatty acids for enhanced potency.
CAS:
137668-62-3
Molecular Weight:
869.001
Purity:
0.98
SMILES:
N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O
References
Shamshirian D, Erfani M, Beiki D, Fallahi B, Shafiei M. Development of a (99m)Tc-labeled lactam bridge-cyclized alpha-MSH derivative peptide as a possible single photon imaging agent for melanoma tumors. Ann Nucl Med. 2015 Oct;29(8):709-20. doi: 10.1007/s12149-015-0998-y. Epub 2015 Jul 8. PubMed PMID: 26152564.
Tammler U, Quillan JM, Lehmann J, Sad?e W, Kassack MU. Design, synthesis, and biological evaluation of non-peptidic ligands at the Xenopus laevis skin-melanocortin receptor. Eur J Med Chem. 2003 May;38(5):481-93. PubMed PMID: 12767598.
Cho MK, Lee CJ, Lee CH, Li SZ, Lim SK, Baik JH, Lee W. Structure and function of the potent cyclic and linear melanocortin analogues. J Struct Biol. 2005 Jun;150(3):300-8. Epub 2005 Apr 13. PubMed PMID: 15890278.
Weiss S, Sebben M, Bockaert J. Corticotropin-peptide regulation of intracellular cyclic AMP production in cortical neurons in primary culture. J Neurochem. 1985 Sep;45(3):869-74. PubMed PMID: 2993515.