N-Phthaloylglutamic acid

TargetMol
Product Code: TAR-T33731
Supplier: TargetMol
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TAR-T33731-100mg100mgEnquire
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TAR-T33731-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
N-Phthaloylglutamic acid is a hydrolytic metabolite of thalidomide.
CAS:
08/01/3227
Molecular Weight:
295.24
Purity:
0.98
SMILES:
C(N[C@@H](CCC(O)=O)C(O)=O)(=O)C1=C(C(O)=O)C=CC=C1

References

Attila C, Ueda A, Wood TK. PA2663 (PpyR) increases biofilm formation in Pseudomonas aeruginosa PAO1 through the psl operon and stimulates virulence and quorum-sensing phenotypes. Appl Microbiol Biotechnol. 2008 Feb;78(2):293-307. Epub 2007 Dec 22. PubMed PMID: 18157527. Ramagiri S, Gupte R, Rakov I, Yates CR, Miller DD. Quantitative chiral analysis of phthaloylglutamic acid and related analogs by a single ratio kinetic method using electrospray ionization and matrix-assisted laser desorption techniques. Rapid Commun Mass Spectrom. 2008;22(5):639-46. doi: 10.1002/rcm.3405. PubMed PMID: 18247407. Kenyon BM, Browne F, D'Amato RJ. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization. Exp Eye Res. 1997 Jun;64(6):971-8. PubMed PMID: 9301478. North WG, Fay MJ, Du J, Cleary M, Gallagher JD, McCann FV. Presence of functional NMDA receptors in a human neuroblastoma cell line. Mol Chem Neuropathol. 1997 Jan-Feb;30(1-2):77-94. PubMed PMID: 9138430.