Oseltamivir carboxylate HCl
| Code | Size | Price |
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| TAR-T33827-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T33827-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Oseltamivir carboxylate is an active metabolite of oseltamivir phosphate (Tamiflu).
CAS:
1415963-60-8
Molecular Weight:
320.81
Purity:
0.98
SMILES:
O(C(CC)CC)[C@H]1[C@H](NC(C)=O)[C@@H](N)CC(C(O)=O)=C1.Cl
References
K R, V S. Discovery of Potent Neuraminidase Inhibitors Using a Combination of Pharmacophore-Based Virtual Screening and Molecular Simulation Approach. Appl Biochem Biotechnol. 2017 Oct 23. doi: 10.1007/s12010-017-2625-y. [Epub ahead of print] PubMed PMID: 29063410.
Andreatos N, Mylonakis E. Triple therapy reduced mortality more than oseltamivir alone in patients admitted for severe influenza infection. Ann Intern Med. 2017 Oct 17;167(8):JC41. doi: 10.7326/ACPJC-2017-167-8-041. PubMed PMID: 29049760.
Shen C, Chen J, Li R, Zhang M, Wang G, Stegalkina S, Zhang L, Chen J, Cao J, Bi X, Anderson SF, Alefantis T, Zhang M, Cai X, Yang K, Zheng Q, Fang M, Yu H, Luo W, Zheng Z, Yuan Q, Zhang J, Wai-Kuo Shih J, Kleanthous H, Chen H, Chen Y, Xia N. A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses. Sci Transl Med. 2017 Oct 18;9(412). pii: eaam5752. doi: 10.1126/scitranslmed.aam5752. PubMed PMID: 29046433.
Choi WS, Jeong JH, Kwon JJ, Ahn SJ, Lloren KKS, Kwon HI, Chae HB, Hwang J, Kim MH, Kim CJ, Webby RJ, Govorkova EA, Choi YK, Baek YH, Song MS. Screening for Neuraminidase Inhibitor Resistance Markers among Avian Influenza Viruses of the N4, N5, N6 and N8 Neuraminidase Subtypes. J Virol. 2017 Oct 18. pii: JVI.01580-17. doi: 10.1128/JVI.01580-17. [Epub ahead of print] PubMed PMID: 29046464.