Phenylalanylglutamate

TargetMol
Product Code: TAR-T34019
Supplier: TargetMol
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TAR-T34019-100mg100mgEnquire
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TAR-T34019-500mg500mgEnquire
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

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Further Information

Bioactivity:
Phenylalanylglutamate is a dipeptide composed of phenylalanine and glutamate. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an 'Expected' metabolite.
CAS:
3617-45-6
Formula:
C14H18N2O5
Molecular Weight:
294.3
Purity:
0.98
SMILES:
C([C@@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)N)C1=CC=CC=C1

References

Zaczek R, Arlis S, Markl A, Murphy T, Drucker H, Coyle JT. Characteristics of chloride-dependent incorporation of glutamate into brain membranes argue against a receptor binding site. Neuropharmacology. 1987 Apr;26(4):281-7. PubMed PMID: 2884589. Ferkany J, Zaczek R, Markl A, Coyle JT. Glutamate-containing dipeptides enhance specific binding at glutamate receptors and inhibit specific binding at kainate receptors in rat brain. Neurosci Lett. 1984 Feb 24;44(3):281-6. PubMed PMID: 6328368. Kessler M, Petersen G, Vu HM, Baudry M, Lynch G. L-phenylalanyl-L-glutamate-stimulated, chloride-dependent glutamate binding represents glutamate sequestration mediated by an exchange system. J Neurochem. 1987 Apr;48(4):1191-200. PubMed PMID: 2880930.