RH 421
| Code | Size | Price |
|---|
| TAR-T34313-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34313-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
RH 421 is an amphiphilic styryl dye.
CAS:
107610-19-5
Molecular Weight:
498.72
Purity:
0.98
SMILES:
O=S(=O)([O-])CCCC[N+]1=CC=C(C=CC=CC2=CC=C(C=C2)N(CCCCC)CCCCC)C=C1
References
Mikha?lova EV, Efimova SS, Ostroumova OS. [The effects of RH 421 on the activity of amphotericin B in cell and model membranes]. Tsitologiia. 2013;55(2):136-9. Russian. PubMed PMID: 23718076.
Chulkov EG, Schagina LV, Ostroumova OS. Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore. Biochim Biophys Acta. 2015 Jan;1848(1 Pt A):192-9. doi: 10.1016/j.bbamem.2014.09.004. Epub 2014 Sep 16. PubMed PMID: 25223717.
Apetrei A, Mereuta L, Luchian T. The RH 421 styryl dye induced, pore model-dependent modulation of antimicrobial peptides activity in reconstituted planar membranes. Biochim Biophys Acta. 2009 Aug;1790(8):809-16. doi: 10.1016/j.bbagen.2009.04.002. Epub 2009 Apr 9. PubMed PMID: 19362116.
Ostroumova OS, Efimova SS, Mikhailova EV, Schagina LV. The interaction of dipole modifiers with amphotericin-ergosterol complexes. Effects of phospholipid and sphingolipid membrane composition. Eur Biophys J. 2014 May;43(4-5):207-15. doi: 10.1007/s00249-014-0946-0. Epub 2014 Feb 23. PubMed PMID: 24563224.