Rugulin
| Code | Size | Price |
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| TAR-T34447-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34447-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Rugulin is a minor metabolite from Penicillium rugulosum and a naturally occurring bisanthraquinone.
CAS:
67278-88-0
Molecular Weight:
568.534
Purity:
0.98
SMILES:
COC1C2C3C(OC)C4C(=O)C56C(=O)c7c(O)cc(C)cc7C(=O)C35C1C(=O)C61C(=O)c3c(O)cc(C)cc3C(=O)C241 |TLB:39:41:26:11.24,29:28:2:4.24,8:41:26:11.24,22:24:2:28.26.41,THB:1:2:26:11.24,4:3:26:11.24,5:4:2:28.26.41,8:41:2:4.24,11:28:2:4.24,11:24:2:28.26.41|
References
Nicolaou KC, Lim YH, Piper JL, Papageorgiou CD. Total syntheses of 2,2'-epi-cytoskyrin A, rugulosin, and the alleged structure of rugulin. J Am Chem Soc. 2007 Apr 4;129(13):4001-13. Epub 2007 Mar 14. PubMed PMID: 17355133.
Nicolaou KC, Papageorgiou CD, Piper JL, Chadha RK. The cytoskyrin cascade: a facile entry into cytoskyrin A, deoxyrubroskyrin, rugulin, skyrin, and flavoskyrin model systems. Angew Chem Int Ed Engl. 2005 Sep 12;44(36):5846-51. PubMed PMID: 16123947.
Sedmera P, Podojil M, Vokoun J, Betina V, Nemec P. 2,2'-dimethoxy-4a,4a'-dehydrorugulosin (rugulin), a minor metabolite from Penicillium rugulosum. Folia Microbiol (Praha). 1978;23(1):64-7. PubMed PMID: 564320.
Krivobok S, Seigle-Murandi F, Steiman R, Marzin DR, Betina V. Mutagenicity of substituted anthraquinones in the Ames/Salmonella microsome system. Mutat Res. 1992 May 1;279(1):1-8. PubMed PMID: 1374527.