Sarcolysine acridine
| Code | Size | Price |
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| TAR-T34524-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34524-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
Sarcolysine acridine is a bioactive chemical.
CAS:
53161-31-2
Molecular Weight:
518.86
Purity:
0.98
SMILES:
N([C@@H](CC1=CC=C(N(CCCl)CCCl)C=C1)C(O)=O)C=2C3=C(N=C4C2C=CC=C4)C=CC=C3.Cl
References
Cao J, Lin G, Gong Y, Pan P, Ma Y, Huang P, Ying M, Hou T, He Q, Yang B. DNA-PKcs, a novel functional target of acriflavine, mediates acriflavine's p53-dependent synergistic anti-tumor efficiency with melphalan. Cancer Lett. 2016 Dec 1;383(1):115-124. doi: 10.1016/j.canlet.2016.09.029. Epub 2016 Sep 29. PubMed PMID: 27693638.
Iordanski? AB, Prokof'eva-Bel'govska, Badaev NS, Kolosova MO, Zelenin AV. [Detection of specific fractions in heterochromatin by means of sarcolysine acridine]. Dokl Akad Nauk SSSR. 1971 Nov 1;201(1):213-6. Russian. PubMed PMID: 5002203.
Kim M, Blum AB, Haslinger ML, Donahue MJ, Fisher DT, Skitzki JJ, Park IY. Quinacrine for extremity melanoma in a mouse model of isolated limb perfusion (ILP). Surg Today. 2015 Mar;45(3):355-62. doi: 10.1007/s00595-014-0952-y. Epub 2014 Jul 8. PubMed PMID: 24998594.
Joubert JP, Smit FJ, du Plessis L, Smith PJ, N'Da DD. Synthesis and in vitro biological evaluation of aminoacridines and artemisinin-acridine hybrids. Eur J Pharm Sci. 2014 Jun 2;56:16-27. doi: 10.1016/j.ejps.2014.01.014. Epub 2014 Feb 18. PubMed PMID: 24560941.