SK&F 107461

TargetMol
Product Code: TAR-T34650
Supplier: TargetMol
CodeSizePrice
TAR-T34650-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T34650-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C

Images

1 / 1

Further Information

Bioactivity:
F 107461 is a hydroxyethylene dipeptide isostere.
CAS:
126380-03-8
Molecular Weight:
711.84
Purity:
0.98
SMILES:
[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC(OCC2=CC=CC=C2)=O)C)=O)C)=O)[C@H](CCC(N[C@H](C(N[C@H](C(OC)=O)C(C)C)=O)[C@@H](C)C)=O)O

References

Potts W, van Horn R, Anderson K, Blake T, Garver E, Joseph G, Dreyer G, Shu A, Heys R, Fong KL. Characterization of the metabolites of the peptidomimetic human immunodeficiency virus type 1 protease inhibitor SK&F 107461 in rats using liquid chromatography/mass spectrometry. Drug Metab Dispos. 1995 Aug;23(8):799-805. PubMed PMID: 7493545. Bugelski PJ, Kaplan JM, Hart TK, Miller J, Laydon JT, Lee JC, Dreyer GB, Kirsh R. Effect of a human immunodeficiency virus protease inhibitor on human monocyte function. AIDS Res Hum Retroviruses. 1992 Dec;8(12):1951-8. PubMed PMID: 1493045.