SK&F 39728-A
| Code | Size | Price |
|---|
| TAR-T34652-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34652-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
SK&F 39728-A is a bioactive chemical.
CAS:
3549-17-5
Formula:
C17H18F3NO
Molecular Weight:
309.33
Purity:
0.98
SMILES:
FC(F)(F)C=1C=CC=C(C1)C(OC)CNCC=2C=CC=CC2
References
Adelman JP. SK channels and calmodulin. Channels (Austin). 2016;10(1):1-6. doi: 10.1080/19336950.2015.1029688. Epub 2015 May 5. Review. PubMed PMID: 25942650; PubMed Central PMCID: PMC4802798.
Ye Y, Huang X, Zhang Y, Lai X, Wu X, Zeng X, Tang X, Zeng Y. Calcium influx blocked by SK&F 96365 modulates the LPS plus IFN-?-induced inflammatory response in murine peritoneal macrophages. Int Immunopharmacol. 2012 Feb;12(2):384-93. doi: 10.1016/j.intimp.2011.12.011. Epub 2011 Dec 31. PubMed PMID: 22212354.
Park EJ, Kim SY, Kim SH, Lee CR, Kim IS, Park JK, Lee SW, Kim BJ, Chun JN, So I, Jeon JH. SK&F 96365 induces apoptosis and autophagy by inhibiting Akt-mTOR signaling in A7r5 cells. Biochim Biophys Acta. 2011 Dec;1813(12):2157-64. doi: 10.1016/j.bbamcr.2011.06.021. Epub 2011 Jul 13. PubMed PMID: 21767581.
Benson GM, Alston DR, Hickey DM, Jaxa-Chamiec AA, Whittaker CM, Haynes C, Glen A, Blanchard S, Cresswell SR, Suckling KE. SK&F 97426-A: a novel bile acid sequestrant with higher affinities and slower dissociation rates for bile acids in vitro than cholestyramine. J Pharm Sci. 1997 Jan;86(1):76-81. PubMed PMID: 9002463.