S-MGB-234 TFA
Code | Size | Price |
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TAR-T34663-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T34663-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Images
Documents
Further Information
Bioactivity:
S-MGB-234 is a novel Minor Groove Binder that cures animal African trypanosomiasis in an in vivo mouse model. S-MGB-234 has significant potential as novel therapeutic agents for animal African trypanosomiasis.
CAS:
1970223-54-1
Molecular Weight:
796.67
Purity:
0.98
SMILES:
OC(C(F)(F)F)=O.O=C(C1=CC(NC(C2=CN=C(/C=C/C3=CC=C(C=C3)OC)C=C2)=O)=CN1C)NC4=CN(C)C(C(NCCC(N)=N)=O)=C4.OC(C(F)(F)F)=O
References
Giordani F, Khalaf AI, Gillingwater K, Munday JC, de Koning HP, Suckling CJ, Barrett MP, Scott FJ. Novel Minor Groove Binders cure animal African trypanosomiasis in an in vivo mouse model. J Med Chem. 2019 Feb 14. doi: 10.1021/acs.jmedchem.8b01847. [Epub ahead of print] PubMed PMID: 30763102.