TAN67
| Code | Size | Price |
|---|
| TAR-T34784-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34784-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
TAN67 is the first effective selective non-peptide delta1 opioid receptor.
CAS:
1217628-73-3
Molecular Weight:
506.282
Purity:
0.98
SMILES:
Br.Br.[H][C@]12CN(C)CC[C@@]1(Cc1nc3ccccc3cc1C2)c1cccc(O)c1
References
Ohsawa M, Nagase H, Kamei J. Role of intracellular calcium in modification of mu and delta opioid receptor-mediated antinociception by diabetes in mice. J Pharmacol Exp Ther. 1998 Aug;286(2):780-7. PubMed PMID: 9694934.
Quock RM, Hosohata Y, Knapp RJ, Burkey TH, Hosohata K, Zhang X, Rice KC, Nagase H, Hruby VJ, Porreca F, Roeske WR, Yamamura HI. Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. Eur J Pharmacol. 1997 May 12;326(1):101-4. PubMed PMID: 9178661.
Martin NA, Prather PL. Interaction of co-expressed mu- and delta-opioid receptors in transfected rat pituitary GH(3) cells. Mol Pharmacol. 2001 Apr;59(4):774-83. PubMed PMID: 11259622.
Burford NT, Livingston KE, Canals M, Ryan MR, Budenholzer LM, Han Y, Shang Y, Herbst JJ, O'Connell J, Banks M, Zhang L, Filizola M, Bassoni DL, Wehrman TS, Christopoulos A, Traynor JR, Gerritz SW, Alt A. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the ?-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9. doi: 10.1021/acs.jmedchem.5b00007. Epub 2015 May 7. PubMed PMID: 25901762; PubMed Central PMCID: PMC4703104.