TCCP
| Code | Size | Price |
|---|
| TAR-T34791-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T34791-500mg | 500mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20°C
Documents
Further Information
Bioactivity:
TCCP is a natural inducer of apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
CAS:
T34791
Molecular Weight:
379.54
Purity:
0.98
SMILES:
O=C(C1=CNC=C1C(OCC(CCCC)CC)=O)OCC(CC)CCCC
References
Rashmi KC, Atreya HS, Harsha Raj M, Salimath BP, Aparna HS. A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1. Cell Stress Chaperones. 2017 Sep;22(5):751-766. doi: 10.1007/s12192-017-0802-0. Epub 2017 Jul 17. PubMed PMID: 28717943; PubMed Central PMCID: PMC5573693.
Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity. Chem Biol Interact. 2019 Feb 1;299:120-130. doi: 10.1016/j.cbi.2018.12.005. Epub 2018 Dec 10. PubMed PMID: 30543781.